Reliability of the transcranial Doppler ultrasound-derived mean flow index for assessing dynamic cerebral autoregulation in healthy volunteers

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Reliability of the transcranial Doppler ultrasound-derived mean flow index for assessing dynamic cerebral autoregulation in healthy volunteers. / Riberholt, Christian Gunge; Olsen, Markus Harboe; Skovgaard, Lene Theil; Berg, Ronan M.G.; Møller, Kirsten; Mehlsen, Jesper.

I: Medical Engineering and Physics, Bind 89, 2021, s. 1-6.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Riberholt, CG, Olsen, MH, Skovgaard, LT, Berg, RMG, Møller, K & Mehlsen, J 2021, 'Reliability of the transcranial Doppler ultrasound-derived mean flow index for assessing dynamic cerebral autoregulation in healthy volunteers', Medical Engineering and Physics, bind 89, s. 1-6. https://doi.org/10.1016/j.medengphy.2021.01.003

APA

Riberholt, C. G., Olsen, M. H., Skovgaard, L. T., Berg, R. M. G., Møller, K., & Mehlsen, J. (2021). Reliability of the transcranial Doppler ultrasound-derived mean flow index for assessing dynamic cerebral autoregulation in healthy volunteers. Medical Engineering and Physics, 89, 1-6. https://doi.org/10.1016/j.medengphy.2021.01.003

Vancouver

Riberholt CG, Olsen MH, Skovgaard LT, Berg RMG, Møller K, Mehlsen J. Reliability of the transcranial Doppler ultrasound-derived mean flow index for assessing dynamic cerebral autoregulation in healthy volunteers. Medical Engineering and Physics. 2021;89:1-6. https://doi.org/10.1016/j.medengphy.2021.01.003

Author

Riberholt, Christian Gunge ; Olsen, Markus Harboe ; Skovgaard, Lene Theil ; Berg, Ronan M.G. ; Møller, Kirsten ; Mehlsen, Jesper. / Reliability of the transcranial Doppler ultrasound-derived mean flow index for assessing dynamic cerebral autoregulation in healthy volunteers. I: Medical Engineering and Physics. 2021 ; Bind 89. s. 1-6.

Bibtex

@article{f1dd24ec9cab4130bd52f6e8ed6e65c8,
title = "Reliability of the transcranial Doppler ultrasound-derived mean flow index for assessing dynamic cerebral autoregulation in healthy volunteers",
abstract = "The transcranial Doppler ultrasound-derived mean flow index (Mxa) is widely used for assessing dynamic cerebral autoregulation (dCA) in different clinical populations. This study aimed at estimating the relative and absolute reliability of Mxa in healthy participants in the supine position and during head-up tilt (HUT). Fourteen healthy participants were examined on two separate occasions during which, mean middle cerebral artery blood flow velocity (MCAv), non-invasive blood pressure, and heart rate were continuously recorded in the supine position and during HUT. Mxa was calculated as the correlation coefficient between mean arterial blood pressure and MCAv using either 3-, 5-, or 10-second averages collected over a 300 second period. Intraclass correlation coefficient (ICC1.1) was calculated to assess relative reliability, while the standard error of measurement (SEM), and limits of agreement (LOA) were used to assess absolute reliability. Mxa-based 3-second averages yielded a similar relative and absolute reliability in both positions. When Mxa was calculated from 5-second averages, the most reliable values were obtained during HUT. The poorest reliability was achieved using 10-second averages, regardless of posture. The Mxa shows fair reliability with acceptable LOA in healthy volunteers when based on 3-second averages, both in the supine position and during HUT.",
keywords = "Autoregulatory index, Head-up tilt test, Healthy, ICC, Limits of agreement, Standard error of the measurement",
author = "Riberholt, {Christian Gunge} and Olsen, {Markus Harboe} and Skovgaard, {Lene Theil} and Berg, {Ronan M.G.} and Kirsten M{\o}ller and Jesper Mehlsen",
year = "2021",
doi = "10.1016/j.medengphy.2021.01.003",
language = "English",
volume = "89",
pages = "1--6",
journal = "Medical Engineering & Physics",
issn = "1350-4533",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Reliability of the transcranial Doppler ultrasound-derived mean flow index for assessing dynamic cerebral autoregulation in healthy volunteers

AU - Riberholt, Christian Gunge

AU - Olsen, Markus Harboe

AU - Skovgaard, Lene Theil

AU - Berg, Ronan M.G.

AU - Møller, Kirsten

AU - Mehlsen, Jesper

PY - 2021

Y1 - 2021

N2 - The transcranial Doppler ultrasound-derived mean flow index (Mxa) is widely used for assessing dynamic cerebral autoregulation (dCA) in different clinical populations. This study aimed at estimating the relative and absolute reliability of Mxa in healthy participants in the supine position and during head-up tilt (HUT). Fourteen healthy participants were examined on two separate occasions during which, mean middle cerebral artery blood flow velocity (MCAv), non-invasive blood pressure, and heart rate were continuously recorded in the supine position and during HUT. Mxa was calculated as the correlation coefficient between mean arterial blood pressure and MCAv using either 3-, 5-, or 10-second averages collected over a 300 second period. Intraclass correlation coefficient (ICC1.1) was calculated to assess relative reliability, while the standard error of measurement (SEM), and limits of agreement (LOA) were used to assess absolute reliability. Mxa-based 3-second averages yielded a similar relative and absolute reliability in both positions. When Mxa was calculated from 5-second averages, the most reliable values were obtained during HUT. The poorest reliability was achieved using 10-second averages, regardless of posture. The Mxa shows fair reliability with acceptable LOA in healthy volunteers when based on 3-second averages, both in the supine position and during HUT.

AB - The transcranial Doppler ultrasound-derived mean flow index (Mxa) is widely used for assessing dynamic cerebral autoregulation (dCA) in different clinical populations. This study aimed at estimating the relative and absolute reliability of Mxa in healthy participants in the supine position and during head-up tilt (HUT). Fourteen healthy participants were examined on two separate occasions during which, mean middle cerebral artery blood flow velocity (MCAv), non-invasive blood pressure, and heart rate were continuously recorded in the supine position and during HUT. Mxa was calculated as the correlation coefficient between mean arterial blood pressure and MCAv using either 3-, 5-, or 10-second averages collected over a 300 second period. Intraclass correlation coefficient (ICC1.1) was calculated to assess relative reliability, while the standard error of measurement (SEM), and limits of agreement (LOA) were used to assess absolute reliability. Mxa-based 3-second averages yielded a similar relative and absolute reliability in both positions. When Mxa was calculated from 5-second averages, the most reliable values were obtained during HUT. The poorest reliability was achieved using 10-second averages, regardless of posture. The Mxa shows fair reliability with acceptable LOA in healthy volunteers when based on 3-second averages, both in the supine position and during HUT.

KW - Autoregulatory index

KW - Head-up tilt test

KW - Healthy

KW - ICC

KW - Limits of agreement

KW - Standard error of the measurement

U2 - 10.1016/j.medengphy.2021.01.003

DO - 10.1016/j.medengphy.2021.01.003

M3 - Journal article

C2 - 33608119

AN - SCOPUS:85099795520

VL - 89

SP - 1

EP - 6

JO - Medical Engineering & Physics

JF - Medical Engineering & Physics

SN - 1350-4533

ER -

ID: 256628470