Causes of death in children with congenital anomalies up to age 10 in eight European countries

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Causes of death in children with congenital anomalies up to age 10 in eight European countries. / Rissmann, Anke; Tan, Joachim; Glinianaia, Svetlana V; Rankin, Judith; Pierini, Anna; Santoro, Michele; Coi, Alessio; Garne, Ester; Loane, Maria; Given, Joanne; Reid, Abigail; Aizpurua, Amaia; Akhmedzhanova, Diana; Ballardini, Elisa; Barisic, Ingeborg; Cavero-Carbonell, Clara; de Walle, Hermien E K; Gatt, Miriam; Gissler, Mika; Heino, Anna; Jordan, Sue; Urhøj, Stine Kjær; Klungsøyr, Kari; Lutke, Renee; Mokoroa, Olatz; Neville, Amanda Julie; Thayer, Daniel S; Wellesley, Diana G; Yevtushok, Lyubov; Zurriaga, Oscar; Morris, Joan.

I: BMJ Paediatrics Open, Bind 7, Nr. 1, 2023.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Rissmann, A, Tan, J, Glinianaia, SV, Rankin, J, Pierini, A, Santoro, M, Coi, A, Garne, E, Loane, M, Given, J, Reid, A, Aizpurua, A, Akhmedzhanova, D, Ballardini, E, Barisic, I, Cavero-Carbonell, C, de Walle, HEK, Gatt, M, Gissler, M, Heino, A, Jordan, S, Urhøj, SK, Klungsøyr, K, Lutke, R, Mokoroa, O, Neville, AJ, Thayer, DS, Wellesley, DG, Yevtushok, L, Zurriaga, O & Morris, J 2023, 'Causes of death in children with congenital anomalies up to age 10 in eight European countries', BMJ Paediatrics Open, bind 7, nr. 1. https://doi.org/10.1136/bmjpo-2022-001617

APA

Rissmann, A., Tan, J., Glinianaia, S. V., Rankin, J., Pierini, A., Santoro, M., Coi, A., Garne, E., Loane, M., Given, J., Reid, A., Aizpurua, A., Akhmedzhanova, D., Ballardini, E., Barisic, I., Cavero-Carbonell, C., de Walle, H. E. K., Gatt, M., Gissler, M., ... Morris, J. (2023). Causes of death in children with congenital anomalies up to age 10 in eight European countries. BMJ Paediatrics Open, 7(1). https://doi.org/10.1136/bmjpo-2022-001617

Vancouver

Rissmann A, Tan J, Glinianaia SV, Rankin J, Pierini A, Santoro M o.a. Causes of death in children with congenital anomalies up to age 10 in eight European countries. BMJ Paediatrics Open. 2023;7(1). https://doi.org/10.1136/bmjpo-2022-001617

Author

Rissmann, Anke ; Tan, Joachim ; Glinianaia, Svetlana V ; Rankin, Judith ; Pierini, Anna ; Santoro, Michele ; Coi, Alessio ; Garne, Ester ; Loane, Maria ; Given, Joanne ; Reid, Abigail ; Aizpurua, Amaia ; Akhmedzhanova, Diana ; Ballardini, Elisa ; Barisic, Ingeborg ; Cavero-Carbonell, Clara ; de Walle, Hermien E K ; Gatt, Miriam ; Gissler, Mika ; Heino, Anna ; Jordan, Sue ; Urhøj, Stine Kjær ; Klungsøyr, Kari ; Lutke, Renee ; Mokoroa, Olatz ; Neville, Amanda Julie ; Thayer, Daniel S ; Wellesley, Diana G ; Yevtushok, Lyubov ; Zurriaga, Oscar ; Morris, Joan. / Causes of death in children with congenital anomalies up to age 10 in eight European countries. I: BMJ Paediatrics Open. 2023 ; Bind 7, Nr. 1.

Bibtex

@article{c96e0c743fb248a99397084ce70c7d09,

title = "Causes of death in children with congenital anomalies up to age 10 in eight European countries",

abstract = "BACKGROUND: Congenital anomalies (CAs) increase the risk of death during infancy and childhood. This study aimed to evaluate the accuracy of using death certificates to estimate the burden of CAs on mortality for children under 10 years old.METHODS: Children born alive with a major CA between 1 January 1995 and 31 December 2014, from 13 population-based European CA registries were linked to mortality records up to their 10th birthday or 31 December 2015, whichever was earlier.RESULTS: In total 4199 neonatal, 2100 postneonatal and 1087 deaths in children aged 1-9 years were reported. The underlying cause of death was a CA in 71% (95% CI 64% to 78%) of neonatal and 68% (95% CI 61% to 74%) of postneonatal infant deaths. For neonatal deaths the proportions varied by registry from 45% to 89% and by anomaly from 53% for Down syndrome to 94% for tetralogy of Fallot. In children aged 1-9, 49% (95% CI 42% to 57%) were attributed to a CA. Comparing mortality in children with anomalies to population mortality predicts that over 90% of all deaths at all ages are attributable to the anomalies. The specific CA was often not reported on the death certificate, even for lethal anomalies such as trisomy 13 (only 80% included the code for trisomy 13).CONCLUSIONS: Data on the underlying cause of death from death certificates alone are not sufficient to evaluate the burden of CAs on infant and childhood mortality across countries and over time. Linked data from CA registries and death certificates are necessary for obtaining accurate estimates.",

author = "Anke Rissmann and Joachim Tan and Glinianaia, {Svetlana V} and Judith Rankin and Anna Pierini and Michele Santoro and Alessio Coi and Ester Garne and Maria Loane and Joanne Given and Abigail Reid and Amaia Aizpurua and Diana Akhmedzhanova and Elisa Ballardini and Ingeborg Barisic and Clara Cavero-Carbonell and {de Walle}, {Hermien E K} and Miriam Gatt and Mika Gissler and Anna Heino and Sue Jordan and Urh{\o}j, {Stine Kj{\ae}r} and Kari Klungs{\o}yr and Renee Lutke and Olatz Mokoroa and Neville, {Amanda Julie} and Thayer, {Daniel S} and Wellesley, {Diana G} and Lyubov Yevtushok and Oscar Zurriaga and Joan Morris",

note = "{\textcopyright} Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.",

year = "2023",

doi = "10.1136/bmjpo-2022-001617",

language = "English",

volume = "7",

journal = "BMJ Paediatrics Open",

issn = "2399-9772",

publisher = "BMJ Publishing Group",

number = "1",

}

RIS

TY - JOUR

T1 - Causes of death in children with congenital anomalies up to age 10 in eight European countries

AU - Rissmann, Anke

AU - Tan, Joachim

AU - Glinianaia, Svetlana V

AU - Rankin, Judith

AU - Pierini, Anna

AU - Santoro, Michele

AU - Coi, Alessio

AU - Garne, Ester

AU - Loane, Maria

AU - Given, Joanne

AU - Reid, Abigail

AU - Aizpurua, Amaia

AU - Akhmedzhanova, Diana

AU - Ballardini, Elisa

AU - Barisic, Ingeborg

AU - Cavero-Carbonell, Clara

AU - de Walle, Hermien E K

AU - Gatt, Miriam

AU - Gissler, Mika

AU - Heino, Anna

AU - Jordan, Sue

AU - Urhøj, Stine Kjær

AU - Klungsøyr, Kari

AU - Lutke, Renee

AU - Mokoroa, Olatz

AU - Neville, Amanda Julie

AU - Thayer, Daniel S

AU - Wellesley, Diana G

AU - Yevtushok, Lyubov

AU - Zurriaga, Oscar

AU - Morris, Joan

PY - 2023

Y1 - 2023

N2 - BACKGROUND: Congenital anomalies (CAs) increase the risk of death during infancy and childhood. This study aimed to evaluate the accuracy of using death certificates to estimate the burden of CAs on mortality for children under 10 years old.METHODS: Children born alive with a major CA between 1 January 1995 and 31 December 2014, from 13 population-based European CA registries were linked to mortality records up to their 10th birthday or 31 December 2015, whichever was earlier.RESULTS: In total 4199 neonatal, 2100 postneonatal and 1087 deaths in children aged 1-9 years were reported. The underlying cause of death was a CA in 71% (95% CI 64% to 78%) of neonatal and 68% (95% CI 61% to 74%) of postneonatal infant deaths. For neonatal deaths the proportions varied by registry from 45% to 89% and by anomaly from 53% for Down syndrome to 94% for tetralogy of Fallot. In children aged 1-9, 49% (95% CI 42% to 57%) were attributed to a CA. Comparing mortality in children with anomalies to population mortality predicts that over 90% of all deaths at all ages are attributable to the anomalies. The specific CA was often not reported on the death certificate, even for lethal anomalies such as trisomy 13 (only 80% included the code for trisomy 13).CONCLUSIONS: Data on the underlying cause of death from death certificates alone are not sufficient to evaluate the burden of CAs on infant and childhood mortality across countries and over time. Linked data from CA registries and death certificates are necessary for obtaining accurate estimates.

AB - BACKGROUND: Congenital anomalies (CAs) increase the risk of death during infancy and childhood. This study aimed to evaluate the accuracy of using death certificates to estimate the burden of CAs on mortality for children under 10 years old.METHODS: Children born alive with a major CA between 1 January 1995 and 31 December 2014, from 13 population-based European CA registries were linked to mortality records up to their 10th birthday or 31 December 2015, whichever was earlier.RESULTS: In total 4199 neonatal, 2100 postneonatal and 1087 deaths in children aged 1-9 years were reported. The underlying cause of death was a CA in 71% (95% CI 64% to 78%) of neonatal and 68% (95% CI 61% to 74%) of postneonatal infant deaths. For neonatal deaths the proportions varied by registry from 45% to 89% and by anomaly from 53% for Down syndrome to 94% for tetralogy of Fallot. In children aged 1-9, 49% (95% CI 42% to 57%) were attributed to a CA. Comparing mortality in children with anomalies to population mortality predicts that over 90% of all deaths at all ages are attributable to the anomalies. The specific CA was often not reported on the death certificate, even for lethal anomalies such as trisomy 13 (only 80% included the code for trisomy 13).CONCLUSIONS: Data on the underlying cause of death from death certificates alone are not sufficient to evaluate the burden of CAs on infant and childhood mortality across countries and over time. Linked data from CA registries and death certificates are necessary for obtaining accurate estimates.

U2 - 10.1136/bmjpo-2022-001617

DO - 10.1136/bmjpo-2022-001617

M3 - Journal article

C2 - 37353235

VL - 7

JO - BMJ Paediatrics Open

JF - BMJ Paediatrics Open

SN - 2399-9772

IS - 1

ER -

ID: 357471288