Several existing typologies of art-science contain relevant categories for science communication but tend to define art and science in terms of their relationship to one another. This chapter offers a new typology of art-science projects as a novel category in themselves and in terms of their relationship to the world and to the various audiences they serve. Each of the four categories, conveyance, contributive, contextual, and critical, makes sense of art-science works’ roles and their potential in science communication. The examples discussed in each category show the fluidity and flexibility of the projects and demonstrate the value of the categories as tools for understanding art-science, science communication and even science itself.