Prevalence of COPD in Copenhagen
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Prevalence of COPD in Copenhagen. / Fabricius, Peder; Løkke, Anders; Marott, Jacob Louis; Vestbo, Jørgen; Lange, Peter.
I: Respiratory Medicine, Bind 105, Nr. 3, 03.2011, s. 410-7.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Prevalence of COPD in Copenhagen
AU - Fabricius, Peder
AU - Løkke, Anders
AU - Marott, Jacob Louis
AU - Vestbo, Jørgen
AU - Lange, Peter
N1 - Copyright © 2010 Elsevier Ltd. All rights reserved.
PY - 2011/3
Y1 - 2011/3
N2 - INTRODUCTION: COPD is a leading cause of death worldwide; however, prevalence estimates have varied considerably in previous studies. This study aimed to determine the prevalence and severity of COPD in Copenhagen using data from the 4th examination of The Copenhagen City Heart Study, to investigate the relationship between tobacco consumption and COPD, and to characterize the subjects with COPD with regard to BMI, dyspnoea, treatment with respiratory medication and co-morbidities.METHODS: 6236 people participated. All non-asthmatic participants aged 35 years or older with adequate lung function data were included for the final prevalence analyses (n = 5,299). COPD staging was done according to the GOLD criteria.RESULTS: The overall prevalence of COPD was 17.4%. The prevalence increased with age and was higher among males. 6.2% had mild COPD, 9.2% had moderate COPD, and 2.0% had severe or very severe COPD. Tobacco consumption was closely linked to both prevalence and disease severity. Subjects with COPD had lower mean Body Mass Index (BMI) and more frequently a BMI < 21 kg/m(2). Dyspnoea was correlated to lung function but a substantial number of participants with severe COPD experienced no dyspnoea. Only a minority of subjects with COPD received pulmonary medication. COPD was associated with cardiovascular disease and cancer.CONCLUSION: The prevalence of COPD in Denmark is among the highest in the world. It is closely correlated to smoking and age. It is accompanied by substantial co-morbidity and it is grossly under treated.
AB - INTRODUCTION: COPD is a leading cause of death worldwide; however, prevalence estimates have varied considerably in previous studies. This study aimed to determine the prevalence and severity of COPD in Copenhagen using data from the 4th examination of The Copenhagen City Heart Study, to investigate the relationship between tobacco consumption and COPD, and to characterize the subjects with COPD with regard to BMI, dyspnoea, treatment with respiratory medication and co-morbidities.METHODS: 6236 people participated. All non-asthmatic participants aged 35 years or older with adequate lung function data were included for the final prevalence analyses (n = 5,299). COPD staging was done according to the GOLD criteria.RESULTS: The overall prevalence of COPD was 17.4%. The prevalence increased with age and was higher among males. 6.2% had mild COPD, 9.2% had moderate COPD, and 2.0% had severe or very severe COPD. Tobacco consumption was closely linked to both prevalence and disease severity. Subjects with COPD had lower mean Body Mass Index (BMI) and more frequently a BMI < 21 kg/m(2). Dyspnoea was correlated to lung function but a substantial number of participants with severe COPD experienced no dyspnoea. Only a minority of subjects with COPD received pulmonary medication. COPD was associated with cardiovascular disease and cancer.CONCLUSION: The prevalence of COPD in Denmark is among the highest in the world. It is closely correlated to smoking and age. It is accompanied by substantial co-morbidity and it is grossly under treated.
KW - Cardiovascular Diseases
KW - Denmark
KW - Dyspnea
KW - Female
KW - Forced Expiratory Volume
KW - Humans
KW - Male
KW - Middle Aged
KW - Neoplasms
KW - Prevalence
KW - Pulmonary Disease, Chronic Obstructive
KW - Severity of Illness Index
KW - Smoking
KW - Surveys and Questionnaires
U2 - 10.1016/j.rmed.2010.09.019
DO - 10.1016/j.rmed.2010.09.019
M3 - Journal article
C2 - 20952174
VL - 105
SP - 410
EP - 417
JO - Respiratory Medicine
JF - Respiratory Medicine
SN - 0954-6111
IS - 3
ER -
ID: 161393325