Familial atrial fibrillation predicts increased risk of mortality: A study in Danish twins

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Familial atrial fibrillation predicts increased risk of mortality: A study in Danish twins. / Christophersen, Ingrid Elisabeth; Budtz-Joergensen, Esben; Olesen, Morten S.; Haunsø, Stig; Christensen, Kaare; Svendsen, Jesper Hastrup.

I: Circulation: Arrhythmia and Electrophysiology, Bind 6, Nr. 1, 2013, s. 10-15.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Christophersen, IE, Budtz-Joergensen, E, Olesen, MS, Haunsø, S, Christensen, K & Svendsen, JH 2013, 'Familial atrial fibrillation predicts increased risk of mortality: A study in Danish twins', Circulation: Arrhythmia and Electrophysiology, bind 6, nr. 1, s. 10-15. https://doi.org/10.1161/CIRCEP.112.971580

APA

Christophersen, I. E., Budtz-Joergensen, E., Olesen, M. S., Haunsø, S., Christensen, K., & Svendsen, J. H. (2013). Familial atrial fibrillation predicts increased risk of mortality: A study in Danish twins. Circulation: Arrhythmia and Electrophysiology, 6(1), 10-15. https://doi.org/10.1161/CIRCEP.112.971580

Vancouver

Christophersen IE, Budtz-Joergensen E, Olesen MS, Haunsø S, Christensen K, Svendsen JH. Familial atrial fibrillation predicts increased risk of mortality: A study in Danish twins. Circulation: Arrhythmia and Electrophysiology. 2013;6(1):10-15. https://doi.org/10.1161/CIRCEP.112.971580

Author

Christophersen, Ingrid Elisabeth ; Budtz-Joergensen, Esben ; Olesen, Morten S. ; Haunsø, Stig ; Christensen, Kaare ; Svendsen, Jesper Hastrup. / Familial atrial fibrillation predicts increased risk of mortality: A study in Danish twins. I: Circulation: Arrhythmia and Electrophysiology. 2013 ; Bind 6, Nr. 1. s. 10-15.

Bibtex

@article{196756fc0cb545e1baa9246958bfdc9f,
title = "Familial atrial fibrillation predicts increased risk of mortality: A study in Danish twins",
abstract = "Background- Atrial fibrillation (AF) is a common arrhythmia. Several studies have shown association of genetic variants with AF and that familial AF increases the risk of AF. We have previously shown a substantial heritability of AF in a twin study. The objective of this study was to determine whether having a co-twin with AF influences mortality. Methods and Results- We identified all Danish twins with AF born during and after 1912 in the Danish Twin Registry, the National Patient Registry, and the Central Office of Civil Registration. For each twin, we randomly identified 4 twins without AF, matched on sex, zygosity, and age. We compared survival among the co-twins of the affected twins (co-cases, n=2164) and the co-twins of the unaffected twins (co-controls, n=8626). The co-cases showed increased death rates compared with the co-controls (hazard ratio, 1.20; 95% confidence interval, 1.11-1.30; P",
keywords = "Atrial fibrillation, Epidemiology, Genetics, Mortality, Twin study",
author = "Christophersen, {Ingrid Elisabeth} and Esben Budtz-Joergensen and Olesen, {Morten S.} and Stig Hauns{\o} and Kaare Christensen and Svendsen, {Jesper Hastrup}",
year = "2013",
doi = "10.1161/CIRCEP.112.971580",
language = "English",
volume = "6",
pages = "10--15",
journal = "Circulation: Arrhythmia and Electrophysiology",
issn = "1941-3149",
publisher = "Lippincott Williams & Wilkins",
number = "1",

}

RIS

TY - JOUR

T1 - Familial atrial fibrillation predicts increased risk of mortality: A study in Danish twins

AU - Christophersen, Ingrid Elisabeth

AU - Budtz-Joergensen, Esben

AU - Olesen, Morten S.

AU - Haunsø, Stig

AU - Christensen, Kaare

AU - Svendsen, Jesper Hastrup

PY - 2013

Y1 - 2013

N2 - Background- Atrial fibrillation (AF) is a common arrhythmia. Several studies have shown association of genetic variants with AF and that familial AF increases the risk of AF. We have previously shown a substantial heritability of AF in a twin study. The objective of this study was to determine whether having a co-twin with AF influences mortality. Methods and Results- We identified all Danish twins with AF born during and after 1912 in the Danish Twin Registry, the National Patient Registry, and the Central Office of Civil Registration. For each twin, we randomly identified 4 twins without AF, matched on sex, zygosity, and age. We compared survival among the co-twins of the affected twins (co-cases, n=2164) and the co-twins of the unaffected twins (co-controls, n=8626). The co-cases showed increased death rates compared with the co-controls (hazard ratio, 1.20; 95% confidence interval, 1.11-1.30; P

AB - Background- Atrial fibrillation (AF) is a common arrhythmia. Several studies have shown association of genetic variants with AF and that familial AF increases the risk of AF. We have previously shown a substantial heritability of AF in a twin study. The objective of this study was to determine whether having a co-twin with AF influences mortality. Methods and Results- We identified all Danish twins with AF born during and after 1912 in the Danish Twin Registry, the National Patient Registry, and the Central Office of Civil Registration. For each twin, we randomly identified 4 twins without AF, matched on sex, zygosity, and age. We compared survival among the co-twins of the affected twins (co-cases, n=2164) and the co-twins of the unaffected twins (co-controls, n=8626). The co-cases showed increased death rates compared with the co-controls (hazard ratio, 1.20; 95% confidence interval, 1.11-1.30; P

KW - Atrial fibrillation

KW - Epidemiology

KW - Genetics

KW - Mortality

KW - Twin study

U2 - 10.1161/CIRCEP.112.971580

DO - 10.1161/CIRCEP.112.971580

M3 - Journal article

C2 - 23255276

VL - 6

SP - 10

EP - 15

JO - Circulation: Arrhythmia and Electrophysiology

JF - Circulation: Arrhythmia and Electrophysiology

SN - 1941-3149

IS - 1

ER -

ID: 136715981