DNA incorporation of 6-thioguanine nucleotides during maintenance therapy of childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
DNA incorporation of 6-thioguanine nucleotides during maintenance therapy of childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma. / Hedeland, Rikke L; Hvidt, Kristian; Nersting, Jacob; Rosthøj, Susanne; Dalhoff, Kim; Lausen, Birgitte; Schmiegelow, Kjeld.
I: Cancer Chemotherapy and Pharmacology, Bind 66, Nr. 3, 01.08.2010, s. 485-91.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - DNA incorporation of 6-thioguanine nucleotides during maintenance therapy of childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma
AU - Hedeland, Rikke L
AU - Hvidt, Kristian
AU - Nersting, Jacob
AU - Rosthøj, Susanne
AU - Dalhoff, Kim
AU - Lausen, Birgitte
AU - Schmiegelow, Kjeld
PY - 2010/8/1
Y1 - 2010/8/1
N2 - To explore the DNA incorporation of 6-thioguanine nucleotide levels (DNA-6TGN) during 6-mercaptopurine (6MP) therapy of childhood acute lymphoblastic leukaemia (ALL) and non-Hodgkin lymphoma (NHL) and its relation to erythrocyte levels of their metabolites: 6-thioguanine-nucleotides (E-6TGN), methylated metabolites (E-MeMP), Methotrexate polyglutamates (E-MTX), and to thiopurine methyltransferase activity (TPMT).
AB - To explore the DNA incorporation of 6-thioguanine nucleotide levels (DNA-6TGN) during 6-mercaptopurine (6MP) therapy of childhood acute lymphoblastic leukaemia (ALL) and non-Hodgkin lymphoma (NHL) and its relation to erythrocyte levels of their metabolites: 6-thioguanine-nucleotides (E-6TGN), methylated metabolites (E-MeMP), Methotrexate polyglutamates (E-MTX), and to thiopurine methyltransferase activity (TPMT).
KW - 6-Mercaptopurine
KW - Antineoplastic Combined Chemotherapy Protocols
KW - Child
KW - Child, Preschool
KW - Cytosol
KW - DNA
KW - Drug Monitoring
KW - Erythrocytes
KW - Female
KW - Guanine Nucleotides
KW - Humans
KW - Infant
KW - Lymphoma, Non-Hodgkin
KW - Male
KW - Methotrexate
KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma
KW - Purines
KW - Thionucleotides
U2 - 10.1007/s00280-009-1184-5
DO - 10.1007/s00280-009-1184-5
M3 - Journal article
C2 - 19956952
VL - 66
SP - 485
EP - 491
JO - Cancer Chemotherapy and Pharmacology, Supplement
JF - Cancer Chemotherapy and Pharmacology, Supplement
SN - 0943-9404
IS - 3
ER -
ID: 33769619