Lifestyle disease – Københavns Universitet

Lifestyle disease


The number of people with lifestyle diseases is increasing dramatically in these years and there is a need for developing new and sustainable rehabilitation regimes to deal with the increasing problem. The wellbeing of people with lifestyle related chronic diseases (e.g. diabetes, COPD, cancer, cardio-vaskular and musculo-skeletal diseases) and elderly is the main focus of our research group (CopenRehab) with specific focus on the effect of physical activity in a life lone perspective. A sustained habit change is needed to increase the wellbeing in this growing number of citizens with chronic conditions.

A: Diabetes - InterWalk. How can technology be used to keep diabetic citizens motivated and physical active? In collaboration with the Municipality of Copenhagen, the long-term (12 months) effects of a 12 weeks rehab program for type2 diabetics using interval walking delivered via the app InterWalk is tested in a large randomized controlled trail. The advantages of an app-based rehab program are also tested in a user-centred qualitative study. The motivation and adherence to the program is also determined.

Contacts:  Laura Valentiner, Henning Langberg

B: Diabetes – U-Turn2. The effect of 12 months of radical changes in lifestyle (high-frequent exercise, diet, sleep) on the pathology of the disease (e.g. blood sugar), use of medicine and parameters related to motivation and wellbeing (sleep quality) is tested in a large RCT on type2 diabetics in collaboration with Trygfondens Center for Aktiv Sundhed (

Contacts:  Chris MacDonald, Natasja Jensen, Henning Langberg

C: Diabetes - Nem Diabetes2. Digital solution to improve self-efficacy in socially vulnerable type2 diabetics. Based on qualitative interviews with vulnerable type2 diabetics a new app is developed with tailored interface to improve the self-efficacy and increase the motivation for lifestyle changes. The effect on both pathology, lifestyle and motivation and wellbeing is measured

Contacts:  Anne Sophie Mikkelsen (Rigshospitalet), Henning Langberg

D: Diabetes – Family Involvement in diabetics with non-western backgrounds. The importance of involving the family as recourse persons in the implementation of a healthy lifestyle in type2 diabetics is tested in this large RCT. Selected family members and the patient will receive a weekly SMS message through a 12 months period to remind the patient to take his medication and follow the health recommendations (exercise and diet) as described by the nurse. The effects on health care parameters are determined. This project is conducted in collaboration with Bispebjerg Hospital and Municipality of Copenhagen

Contacts:  Caroline Raun, Mette Zander, Hans Perril (Bispebjerg Hospital), Henning Langberg

E: Lung Cancer – PROLUCA. Early rehabilitation (exercise 2 weeks post op) is expected to enhance the physical condition, reduce symptoms and increase the ability to sustain an active lifestyle in newly operated lung cancer patients. The effect is tested in a large RCT in collaboration with Rigshospitalet and Center for Kræft og Sundhed København.  

Contacts:  Maja S. Sommer, Henning Langberg

F: Cardio-vascular diseases - CopenHeart. To identify whether the effect of cardiac rehabilitation in patients with various types of heart diseases depends on context in which the rehabilitation is performed. In collaboration with CopenHeart (Rigshospitalet) and a number of municipalities around Copenhagen 4 large RCTs are performed comparing the effect of rehabilitation conducted in the hospital, in the municipality or in the patient's home. Pulse and diaries are used to monitor the training load independent of context.

Contacts:  Lars H. Tang, Henning Langberg

G: Stroke, Copenhagen Women Study. The main focus in rehabilitation of stroke patients is currently on walking function, whereas hand function is often overlooked. This project uses a special program developed for iPad to practice fine motor skills of stroke patients in a municipality setting. The aim of the project is to investigate the functional effect of training on the iPad as well as citizens' motivation for adopting this approach. The mechanisms underpinning our ability to (re)acquire motor skills, will also be illuminated, just as the involvement of various areas in the brain.

Contacts:  Lisbeth H. Larsen, Henning Langberg

H: Low back pain and risk of sick leave – TIKI. The purpose of TIKI project is to investigate whether it is possible via an early coordinated intersectoral rehabilitation action to prevent absenteeism from work in people with low back pain. The large RCT is performed in collaboration with Municipality of Copenhagen.

Contacts:  Annette Fisker, Tom Pedersen, Henning Langberg

I: COPD – home based rehabilitation. COPD patients are often fatigued as the result of the transportation to the rehabilitation centre reducing the effect of the rehabilitation (exercise). The goal is to ensure lifelong physical activity and self-efficacy. The patients' needs are addressed by means of qualitative interviews with COPD patients and GPs. The information is used to develop an app, which can be used for monitoring the disease state, perform patient education and act as a training aid. The goal is to increase physical activity and function in this patient group.

Contacts:  Katrine Molin, Henning Langberg

J: Amputation – Veterans. In order to optimize the rehabilitation of leg amputated Danish soldiers (veterans) who have been injured on international missions their current maximal oxygen uptake and self-assessed physical function is determined. The goal is to optimize the rehabilitation of wounded from the Armed Forces' international operations. The project also value for rehabilitation of civilians with amputations.

Contacts:  Jan Christensen, Henning Langberg

K: Measuring motivation and wellbeing. A theoretic framework is developed for the understanding and determination of states of motivation, wellbeing and personality across the different intervention studies performed in our research group. A number of questionnaires are translated and validated. Motivation is expected to be a key factor important for the sustained adherence to exercise programs and rehabilitation regimes.

Contacts:  Natasja K. Jensen, Tina Juul-Sørensen, Henning Langberg

L: PROMIS - Translation and validation of new tool for measuring physical function. PROMIS is a tem-bank on physical function developed to monitor physical function. Item bank is developed by a major US government research initiative: the Patient Reported Outcomes Measurement Information System (PROMIS). Physical disability is of great importance in rehabilitation and is used as an outcome measure in clinical research. PROMIS will function as patient-reported health outcomes in the Danish context. The form is translated and validated in cooperation with the municipality of Copenhagen.

Contacts:  Christina W. Schnohr, Henning Langberg

M: OPTIMED - Training for elderly medical patients during and after hospitalization. Up to 17% of elderly medical patients at hospital admission self-time function, but after discharge patients need assistance to go. These patients represent a group of citizens that could potentially become dependent as a result of hospitalization. It is therefore essential to prevent the described loss of performance. In collaboration with Hvidovre Hospital established a research project in a randomized design, which deals focused strength training for the elderly medical patient. The training started at the hospital and continued at home four weeks after discharge.

Contacts:  Lars Damkjær, Mette M. Pedersen, Thomas Bandholm (Hvidovre Hospital), Henning Langberg

N: "Rehab at home" - Digital transition training from prevention centres. The aim of the project is to test the implementation of an optimized form of rehabilitation in relation to the transition phase for citizens with chronic illness that in a period coach in a municipal prevention center. To do home training as understandable as possible, each participant will receive an Android tablet with an app that guides the citizen through the training. The evaluation will identify strengths and weaknesses of the concept, both in terms of resources, training and technology.

Contacts:  Morten Zacho, Henning Langberg

O: Socially Shared Physical Activity. The development of a concept - and empirical studies of efficacy and impact of social media enabled physical activity sharing in new public health marketing, monitoring, and management.

Contacts: Kjeld Hansen (CBS), Henning Langberg