TY - JOUR

T1 - The Intracranial Distribution of Gliomas in Relation to Exposure From Mobile Phones

T2 - Analyses From the INTERPHONE Study

AU - Grell, Kathrine

AU - Frederiksen, Kirsten

AU - Schüz, Joachim

AU - Cardis, Elisabeth

AU - Armstrong, Bruce

AU - Siemiatycki, Jack

AU - Krewski, Daniel R

AU - McBride, Mary L

AU - Johansen, Christoffer

AU - Auvinen, Anssi

AU - Hours, Martine

AU - Blettner, Maria

AU - Sadetzki, Siegal

AU - Lagorio, Susanna

AU - Yamaguchi, Naohito

AU - Woodward, Alistair

AU - Tynes, Tore

AU - Feychting, Maria

AU - Fleming, Sarah J

AU - Swerdlow, Anthony J

AU - Andersen, Per K

N1 - © The Author 2016. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

PY - 2016/12/1

Y1 - 2016/12/1

N2 - When investigating the association between brain tumors and use of mobile telephones, accurate data on tumor position are essential, due to the highly localized absorption of energy in the human brain from the radio-frequency fields emitted. We used a point process model to investigate this association using information that included tumor localization data from the INTERPHONE Study (Australia, Canada, Denmark, Finland, France, Germany, Israel, Italy, Japan, New Zealand, Norway, Sweden, and the United Kingdom). Our main analysis included 792 regular mobile phone users diagnosed with a glioma between 2000 and 2004. Similar to earlier results, we found a statistically significant association between the intracranial distribution of gliomas and the self-reported location of the phone. When we accounted for the preferred side of the head not being exclusively used for all mobile phone calls, the results were similar. The association was independent of the cumulative call time and cumulative number of calls. However, our model used reported side of mobile phone use, which is potentially influenced by recall bias. The point process method provides an alternative to previously used epidemiologic research designs when one is including localization in the investigation of brain tumors and mobile phone use.

AB - When investigating the association between brain tumors and use of mobile telephones, accurate data on tumor position are essential, due to the highly localized absorption of energy in the human brain from the radio-frequency fields emitted. We used a point process model to investigate this association using information that included tumor localization data from the INTERPHONE Study (Australia, Canada, Denmark, Finland, France, Germany, Israel, Italy, Japan, New Zealand, Norway, Sweden, and the United Kingdom). Our main analysis included 792 regular mobile phone users diagnosed with a glioma between 2000 and 2004. Similar to earlier results, we found a statistically significant association between the intracranial distribution of gliomas and the self-reported location of the phone. When we accounted for the preferred side of the head not being exclusively used for all mobile phone calls, the results were similar. The association was independent of the cumulative call time and cumulative number of calls. However, our model used reported side of mobile phone use, which is potentially influenced by recall bias. The point process method provides an alternative to previously used epidemiologic research designs when one is including localization in the investigation of brain tumors and mobile phone use.

U2 - 10.1093/aje/kww082

DO - 10.1093/aje/kww082

M3 - Journal article

C2 - 27810856

VL - 184

SP - 818

EP - 828

JO - American Journal of Epidemiology

JF - American Journal of Epidemiology

SN - 0002-9262

IS - 11

ER -