Regulation of blood flow by prostaglandins

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Regulation of blood flow by prostaglandins. / Boushel, Robert Christopher; Langberg, H; Risum, N; Kjaer, M.

I: Current Vascular Pharmacology, Bind 2, Nr. 2, 01.04.2004, s. 191-7.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Boushel, RC, Langberg, H, Risum, N & Kjaer, M 2004, 'Regulation of blood flow by prostaglandins', Current Vascular Pharmacology, bind 2, nr. 2, s. 191-7.

APA

Boushel, R. C., Langberg, H., Risum, N., & Kjaer, M. (2004). Regulation of blood flow by prostaglandins. Current Vascular Pharmacology, 2(2), 191-7.

Vancouver

Boushel RC, Langberg H, Risum N, Kjaer M. Regulation of blood flow by prostaglandins. Current Vascular Pharmacology. 2004 apr. 1;2(2):191-7.

Author

Boushel, Robert Christopher ; Langberg, H ; Risum, N ; Kjaer, M. / Regulation of blood flow by prostaglandins. I: Current Vascular Pharmacology. 2004 ; Bind 2, Nr. 2. s. 191-7.

Bibtex

@article{2b5de77deeed49fb859baade7ea2942b,
title = "Regulation of blood flow by prostaglandins",
abstract = "Prostaglandins (PGs) belong to the family of prostanoids together with thromboxanes and are produced mainly from arachadonic acid by the enzyme cyclooxygenase. PGs are known to stimulate platelet aggregation, mediate inflammation and edema, play a role in bone metabolism and in biological adaptation of connective tissues e.g. tendon. This review covers the role of PG for mediating tissue blood flow at rest and during increases in metabolic demand such as exercise and reactive hyperaemia. There is strong evidence that PGs contribute to elevate blood flow at rest and during reactive hyperaemia in a variety of tissues. Their role for regulating the large increases in muscle blood flow during exercise is less clear which may be explained by redundant mechanisms. Several interactions are known to exist between specific vasodilator substances, and therefore PGs can act in synergy with other substances and contribute to functional hyperaemia. Furthermore, there is evidence for differential, tissue-specific influences of PGs where their influence on blood flow during exercise may be profound.",
keywords = "Animals, Blood Circulation, Clinical Trials as Topic, Exercise, Humans, Hyperemia, Muscle, Skeletal, Prostaglandins, Regional Blood Flow, Rest, Vasodilation, Vasodilator Agents",
author = "Boushel, {Robert Christopher} and H Langberg and N Risum and M Kjaer",
year = "2004",
month = apr,
day = "1",
language = "English",
volume = "2",
pages = "191--7",
journal = "Current Vascular Pharmacology",
issn = "1570-1611",
publisher = "Bentham Science Publishers",
number = "2",

}

RIS

TY - JOUR

T1 - Regulation of blood flow by prostaglandins

AU - Boushel, Robert Christopher

AU - Langberg, H

AU - Risum, N

AU - Kjaer, M

PY - 2004/4/1

Y1 - 2004/4/1

N2 - Prostaglandins (PGs) belong to the family of prostanoids together with thromboxanes and are produced mainly from arachadonic acid by the enzyme cyclooxygenase. PGs are known to stimulate platelet aggregation, mediate inflammation and edema, play a role in bone metabolism and in biological adaptation of connective tissues e.g. tendon. This review covers the role of PG for mediating tissue blood flow at rest and during increases in metabolic demand such as exercise and reactive hyperaemia. There is strong evidence that PGs contribute to elevate blood flow at rest and during reactive hyperaemia in a variety of tissues. Their role for regulating the large increases in muscle blood flow during exercise is less clear which may be explained by redundant mechanisms. Several interactions are known to exist between specific vasodilator substances, and therefore PGs can act in synergy with other substances and contribute to functional hyperaemia. Furthermore, there is evidence for differential, tissue-specific influences of PGs where their influence on blood flow during exercise may be profound.

AB - Prostaglandins (PGs) belong to the family of prostanoids together with thromboxanes and are produced mainly from arachadonic acid by the enzyme cyclooxygenase. PGs are known to stimulate platelet aggregation, mediate inflammation and edema, play a role in bone metabolism and in biological adaptation of connective tissues e.g. tendon. This review covers the role of PG for mediating tissue blood flow at rest and during increases in metabolic demand such as exercise and reactive hyperaemia. There is strong evidence that PGs contribute to elevate blood flow at rest and during reactive hyperaemia in a variety of tissues. Their role for regulating the large increases in muscle blood flow during exercise is less clear which may be explained by redundant mechanisms. Several interactions are known to exist between specific vasodilator substances, and therefore PGs can act in synergy with other substances and contribute to functional hyperaemia. Furthermore, there is evidence for differential, tissue-specific influences of PGs where their influence on blood flow during exercise may be profound.

KW - Animals

KW - Blood Circulation

KW - Clinical Trials as Topic

KW - Exercise

KW - Humans

KW - Hyperemia

KW - Muscle, Skeletal

KW - Prostaglandins

KW - Regional Blood Flow

KW - Rest

KW - Vasodilation

KW - Vasodilator Agents

M3 - Journal article

C2 - 15320520

VL - 2

SP - 191

EP - 197

JO - Current Vascular Pharmacology

JF - Current Vascular Pharmacology

SN - 1570-1611

IS - 2

ER -

ID: 33816660