On pseudo-values for regression analysis in competing risks models.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

For regression on state and transition probabilities in multi-state models Andersen et al. (Biometrika 90:15-27, 2003) propose a technique based on jackknife pseudo-values. In this article we analyze the pseudo-values suggested for competing risks models and prove some conjectures regarding their asymptotics (Klein and Andersen, Biometrics 61:223-229, 2005). The key is a second order von Mises expansion of the Aalen-Johansen estimator which yields an appropriate representation of the pseudo-values. The method is illustrated with data from a clinical study on total joint replacement. In the application we consider for comparison the estimates obtained with the Fine and Gray approach (J Am Stat Assoc 94:496-509, 1999) and also time-dependent solutions of pseudo-value regression equations.
OriginalsprogEngelsk
TidsskriftLifetime Data Analysis
Vol/bind15
Udgave nummer2
Sider (fra-til)241-255
Antal sider15
ISSN1380-7870
StatusUdgivet - 2009

ID: 10020912